Impact Factor
(JCR 2021)
1.564
Recent Publications
Performance of blood concentrates in controlling inflammatory signs and symptoms after lower third molar extractions: an overview
Almeida, Vinícius Lima De; Costa, Marcelo Dias Moreira De Assis; Mesquita, Caio Melo; Vieira, Walbert Andrade; Lima, Rafael Rodrigues; Lima, Livia Bonjardim; Rode, Sigmar De Mello; Paranhos, Luiz Renato; ABSTRACT Purpose: To summarize the available evidence and answer the following question: What is the current knowledge on the performance of blood concentrates in handling sequelae after lower third molar extractions with the evidence available in systematic reviews? Methods: An electronic
Peripheral nerve injury recovery enhanced by ceftriaxone: a preclinical investigation
Gunar, Berkin; Bora, Ejder Saylav; Topkar, Osman Mert; Baysal, Özgür; Shammadli, Ziya; Erbas, Oytun; ABSTRACT Purpose: To evaluate ceftriaxone’s potential in enhancing peripheral nerve injuries (PNIs) recovery. Methods: Thirty male Wistar rats were divided into control (no surgery), vehicle (sciatic nerve injury + 0.9% NaCl), and ceftriaxone (sciatic nerve injury + 50 mg/kg/day ceftriaxone) groups. Treatments were administered intraperitoneally for 12 weeks. Functional recovery was assessed using inclined plane tests
Effect of multiorgan abdominal ischemic preconditioning on experimental kidney transplantation
Abate, Juan Cruz; Marinoff, Ivana Ivanoff; Arnal, Nathalie; Machuca, Mariana; Papa-Gobbi, Rodrigo; Vecchio, Leandro; Rumbo, Martín; Stringa, Pablo; Lausada, Natalia Raquel; ABSTRACT Purpose: To mitigate ischemia-reperfusion injury (IRI) triggered in solid organ transplant procedures, we aimed to evaluate the effects of multi-organ abdominal ischemic preconditioning (MAIP) in the context of renal IRI. Methods: An experimental kidney transplant model was conducted. Rats were divided into three groups: an intervention free basal
Latest news
The result of an experiment with rats brings histopathological and biochemical analysis focusing on the antifibrotic action of PEG 3350 in the case of liver injury induced by MTX and reveals the potential of polyethylene glycol in the fight against hepatotoxicity also caused by other substances that lead to oxidative stress of liver cells.
A drug used for the treatment of epilepsy it has demonstrated epigenetic properties, raising the possibility of use as an adjuvant, associated with chemo and radiotherapy for the treatment of tumors. A study with rats analyzed the inflammatory reaction, angiogenesis and collagen synthesis obtained from oral treatment in a skin lesion model.
By exploring the influence of milk fat globule protein - factor 8 (MFGE8), also known as lactaderin, results obtained through the RhoA/ROCK signaling pathway in an experiment with Sprague Dawley rats point to a decrease in oxidative stress and the inflammatory process, minimizing the impacts caused by trauma by protecting and restoring the barrier function of the intestinal mucosa.
In search of new alternatives for the treatment of portal hypertension, Brazilian researchers develop a pioneering study to validate a model in medium-sized animals, obtaining significant results for the improvement of the techniques applied in cases of gastrointestinal hemorrhage and indicating the direction for advances in diagnostic and therapeutic procedures.
Timeline
17 Sep 1987
SOBRADPEC installation
1989
I Congresso Nacional de Cirurgia Experimental - Maceió/AL
1991
II Congresso Nacional de Cirurgia Experimental - Foz do Iguaçu/PR
17 Sep 1997
SOBRADPEC turns 10 years old
