Ferreira, Claudia Gissi Da Rocha; Ribeiro, André Richter; Finck, Christiane Madrid; Percicote, Ana Paula; Matias, Jorge Eduardo Fouto; ABSTRACT Purpose: Body weight, blood glucose, and hypothalamic ghrelin receptors were monitored in an animal model of obesity after being treated with sleeve gastrectomy. Methods: Forty-two adult male Wistar rats were randomized into two groups: a non-obese group (standard chow); and an obese group, in which obesity was induced by feeding liquid

Tannuri, Ana Cristina Aoun; Kitahara, Victor Kenji Utino; Marum, Alexandre Amatruda; Mola, Bruno; Souza, Daniel Felipe Marcelino; Rodrigues, Lucas Menon; Paes, Vitor Ribeiro; Leite, Katia Ramos Moreira; Serafini, Suellen; Gonçalves, Josiane De Oliveira; Tannuri, Uenis; ABSTRACT Purpose: To verify the differences in the reversibility of renal function and damage in rats of different ages with unilateral ureteral obstruction (UUO). Methods: Sixty rats were divided into three different groups, newborns, young,

Zhu, Yan; Zhang, Yu; Liu, Feiyan; Xiao, Jiao; ABSTRACT Purpose: To examine the protective effect of alpinumisoflavone against streptozotocin (STZ)-induced gestational diabetes mellitus (GDM) in female rats and explored the underlying mechanisms. Methods: Female rats were used in this study, and intraperitoneal administration of STZ (55 mg/kg) was used to induce diabetes. Body weight, blood glucose level, fetuses, placental weight, and placental index were estimated. Oral glucose tolerance test (OGTT)

Barros, Rui Sergio Monteiro De; Santos, Deivid Ramos Dos; Yamaki, Vitor Nagai; Teixeira, Renan Kleber Costa; Valente, André Lopes; Silveira, Tiago Santos; Dias, Carmen Gilda Barroso Tavares; ABSTRACT Purpose: To evaluate the regenerative efficacy of an experimental biodegradable nerve conduit composed of polycaprolactone and açaí-derived polyurethane, used for peripheral nerve repair, in comparison with different reconstructive techniques. Methods: Wistar rats (n = 48) were allocated into six groups (n =

Falco Neto, Wilson; Domingos, Pedro Henrique; Okida, Gabriel Sanchez; Pissolito, João Felipe; Sanches, Pedro Henrique Soubhia; Azevedo, Lucas Ribeiro De; Mourão Junior, Marcelo Oliveira; Sanches, José Antônio; Gragnani, Alfredo; ABSTRACT Purpose: To analyze the geographical distribution of patients treated at a burn treatment unit (BTU) in Catanduva, São Paulo, Brazil, and examine the relationship between geographic and clinical variables. Methods: This is a cross-sectional study that analyzed patients hospitalized for

Abate, Juan Cruz; Marinoff, Ivana Ivanoff; Arnal, Nathalie; Machuca, Mariana; Papa-Gobbi, Rodrigo; Vecchio, Leandro; Rumbo, Martín; Stringa, Pablo; Lausada, Natalia Raquel; ABSTRACT Purpose: To mitigate ischemia-reperfusion injury (IRI) triggered in solid organ transplant procedures, we aimed to evaluate the effects of multi-organ abdominal ischemic preconditioning (MAIP) in the context of renal IRI. Methods: An experimental kidney transplant model was conducted. Rats were divided into three groups: an intervention free basal

Souza, Andrea Pelicia Roso De; Palhares, Raquel; Baltieri, Letícia; Mussi, Ricardo Kalaf; Antunes, Edson; Mello, Glaucia Coelho De; ABSTRACT Purpose: To establish a profile of the inflammatory response in the preoperative and postoperative period of pulmonary resection of patients without postoperative complications, in order to trace the inflammatory profile of lung resection surgery. Methods: Six collections of arterial and venous blood were performed for data analysis, one sample in the

Karaaslanlı, Abdulmutalip; Tuncer, Mehmet Cudi; Aşır, Fırat; Korak, Tuğcan; ABSTRACT Purpose: We aimed to investigate the role of gallic acid treatment on spinal cord tissues after spinal cord injury (SCI) and its relationship with endoplasmic reticulum (ER) stress by histochemical, immunohistochemical, and in-silico techniques. Methods: Thirty female Wistar albino rats were divided into three groups: sham, SCI, and SCI+gallic acid. SCI was induced by dropping a 15-g weight onto the

Oliveira, Evandro Luis Da Cunha; Vicente, Yvone Avalone De Moraes Villela De Andrade; ABSTRACT Purpose: The aims of this work were to induce anorectal anomaly in rat fetuses via the planned administration of ethylenethiourea (ETU), and to study fetuses exhibiting anorectal malformation, as well as apparently normal fetuses submitted to the effect of ETU. Methods: Time-mated pregnant Wistar rats were randomly divided into control and experimental groups. On gestational day