Impact Factor
(JCR 2021)
1.564
Recent Publications
Bacterial nanocellulose/calcium alginate hydrogel for the treatment of burns
Munhoz, Lauriene Luiza De Souza; Guillens, Luiz Carlos; Alves, Beatriz Candido; Nascimento, Maria Gabriela Oliveira Ferreira Do; Meneguin, Andréia Bagliotti; Carbinatto, Fernanda Mansano; Arruda, Gabriela; Barud, Hernane Da Silva; Aro, Andrea De; Casagrande, Laura De Roch; Silveira, Paulo Cesar Lock; Andrade, Thiago Antônio Moretti; Santos, Glaucia Maria Tech Dos; Caetano, Guilherme Ferreira; ABSTRACT Purpose: Bacterial cellulose (BC) has shown high capacity for the treatment of wounds and burns, providing a
Temozolomide alleviates breast carcinoma via the inhibition of EGFR/ERK/ MMP-1 pathway with induction of apoptotic events
Zhu, Weijun; Zhang, Fengjun; Wang, Maoyun; Meng, Shuai; Ren, Fang; Purpose: To evaluate the chemotherapeutic activity of temozolomide counter to mammary carcinoma. Methods: In-vitro anticancer activity has been conducted on MCF7 cells, and mammary carcinoma has been induced in Wistar rats by introduction of 7, 12-Dimethylbenz(a)anthracene (DMBA), which was sustained for 24 weeks. Histopathology, immunohistochemistry, cell proliferation study and apoptosis assay via TUNEL method was conducted to evaluate an antineoplastic
A microscope in your pocket: can smartphones be used to perform microsurgery?
Menezes Neto, Balduino Ferreira De; Magnani, Lucas Vannuchi; Fernandes, Matheus Scuracchio; Brunello, Luis Fernando Spagnuolo; Souza, Thales Fernandes De; Viterbo, Fausto; ABSTRACT Purpose: To evaluate the use of the latest generation smartphone camera in performing arterial microanastomosis in rats. Methods: Ten Wistar rats were divided into 2 groups and underwent anastomosis of the right carotid artery with the aid of magnification from a microscope (group M) and a smartphone camera
Latest news
The result of an experiment with rats brings histopathological and biochemical analysis focusing on the antifibrotic action of PEG 3350 in the case of liver injury induced by MTX and reveals the potential of polyethylene glycol in the fight against hepatotoxicity also caused by other substances that lead to oxidative stress of liver cells.
A drug used for the treatment of epilepsy it has demonstrated epigenetic properties, raising the possibility of use as an adjuvant, associated with chemo and radiotherapy for the treatment of tumors. A study with rats analyzed the inflammatory reaction, angiogenesis and collagen synthesis obtained from oral treatment in a skin lesion model.
By exploring the influence of milk fat globule protein - factor 8 (MFGE8), also known as lactaderin, results obtained through the RhoA/ROCK signaling pathway in an experiment with Sprague Dawley rats point to a decrease in oxidative stress and the inflammatory process, minimizing the impacts caused by trauma by protecting and restoring the barrier function of the intestinal mucosa.
In search of new alternatives for the treatment of portal hypertension, Brazilian researchers develop a pioneering study to validate a model in medium-sized animals, obtaining significant results for the improvement of the techniques applied in cases of gastrointestinal hemorrhage and indicating the direction for advances in diagnostic and therapeutic procedures.
Timeline
17 Sep 1987
SOBRADPEC installation
1989
I Congresso Nacional de Cirurgia Experimental - Maceió/AL
1991
II Congresso Nacional de Cirurgia Experimental - Foz do Iguaçu/PR
17 Sep 1997
SOBRADPEC turns 10 years old
