Impact Factor
(JCR 2021)
1.564
Recent Publications
Sevoflurane attenuates myocardial ischemia/reperfusion injury by up-regulating microRNA-99a and down-regulating BRD4
Bie, Xiaomin;
Ao, Jiying;
Zhu, Degang;
ABSTRACT Purpose: It has been explored that sevoflurane (Sevo) is cardioprotective in myocardial ischemia/reperfusion injury (MI/RI) and mediates microRNA (miRNA) expression that control various physiological systems. Enlightened by that, the work was programmed to decode the mechanism of Sevo and miR-99a with the participation of bromodomain-containing protein 4 (BRD4). Methods: MI/RImodel was established
Systemic and local inflammatory response after implantation of biomaterial in critical bone injuries
Brassolatti, Patricia;
Castro, Cynthia Aparecida De;
Santos, Hugo Leonardo Dos;
Simões, Isabelle Taira;
Almeida-Lopes, Luciana;
Silva, Juliana Virginio Da;
Duarte, Fernanda Oliveira;
Luna, Genoveva Lourdes Flores;
Beck, Wladimir Rafael;
Latest news
- September 9, 2022
The result of an experiment with rats brings histopathological and biochemical analysis focusing on the antifibrotic action of PEG 3350 in the case of liver injury induced by MTX and reveals the potential of polyethylene glycol in the fight against hepatotoxicity also caused by other substances that lead to oxidative stress of liver cells.
- August 29, 2022
A drug used for the treatment of epilepsy it has demonstrated epigenetic properties, raising the possibility of use as an adjuvant, associated with chemo and radiotherapy for the treatment of tumors. A study with rats analyzed the inflammatory reaction, angiogenesis and collagen synthesis obtained from oral treatment in a skin lesion model.
- August 15, 2022
By exploring the influence of milk fat globule protein - factor 8 (MFGE8), also known as lactaderin, results obtained through the RhoA/ROCK signaling pathway in an experiment with Sprague Dawley rats point to a decrease in oxidative stress and the inflammatory process, minimizing the impacts caused by trauma by protecting and restoring the barrier function of the intestinal mucosa.
- June 3, 2022
In search of new alternatives for the treatment of portal hypertension, Brazilian researchers develop a pioneering study to validate a model in medium-sized animals, obtaining significant results for the improvement of the techniques applied in cases of gastrointestinal hemorrhage and indicating the direction for advances in diagnostic and therapeutic procedures.
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Timeline
17 Sep 1987
SOBRADPEC installation
1989
I Congresso Nacional de Cirurgia Experimental - Maceió/AL
1991
II Congresso Nacional de Cirurgia Experimental - Foz do Iguaçu/PR
17 Sep 1997
SOBRADPEC turns 10 years old
