Impact Factor
(JCR 2021)
1.564
Recent Publications
Performance of complementary therapies in controlling inflammatory signs, symptoms, and complications after lower third molar extraction: a bibliometric analysis of the top 100 most-cited articles
Almeida, Vinícius Lima de
Almeida, Vinícius Lima De; Ferraz, Danilo Cassiano; Cabral, Giovanna Miranda; Gobbi, Arthur Henrique; Vieira, Walbert De Andrade; Lima, Lívia Bonjardim; Lima, Rafael Rodrigues; Rode, Sigmar De Mello; Paranhos, Luiz Renato; ABSTRACT Purpose: To conduct a bibliometric analysis of the 100 most-cited articles on the use of complementary therapies for controlling inflammatory signs, symptoms, and complications after lower third molar extraction. Methods: An electronic search was performed on the Web of
Investigation of the effects of nicotinamide mononucleotide on kidney damage in rats with cecal ligation and perforation sepsis model
Arslan, Ayla
Arslan, Ayla; Keleş, Dilek Vural; Parlak, Seçil Nazife; Yakut, Seda; Gündoğdu, Habibe; Arslantürk, İrem; Uzun, Gökçe Bağcı; Karagöz, Berna Öztürk; ABSTRACT Purpose: To evaluate the protective effects of nicotinamide mononucleotide (NMN), a NAD+ precursor, on kidney tissue in rats with sepsis induced by cecal ligation and puncture model. Methods: In this study, 28 female Sprague Dawley rats were randomly divided into four equal groups: control, sham, sepsis, and sepsis+NMN (500
Investigation of the effects of hydroxychloroquine on rats with pulmonary contusion caused by blunt thoracic trauma
Anadolulu, Ali İhsan
Anadolulu, Ali İhsan; Aydöner, Sinem; Pirim, Ahmet; Ozkanli, Seyma; Durakbaşa, Çiğdem Ulukaya; ABSTRACT Purpose: To investigate the early and late effects of hydroxychloroquine (HCQ) on inflammation, fibrosis, and apoptosis in an experimental rat model of pulmonary contusion. Methods: Thirty-five male Wistar albino rats were randomly allocated into five groups (n = 7): control, pulmonary contusion evaluated on day 3 or day 10 (PC-3 and PC-10), and pulmonary contusion treated with
Damage control resuscitation in resource-diverse settings: a survey-based comparison of trauma care practices worldwide
Pacheco, Leticia Stefani
Pacheco, Leticia Stefani; Possiedi, Rafael Dib; Scalea, Thomas Michael; Ribeiro Junior, Marcelo Augusto Fontenelle; ABSTRACT Purpose: Trauma is a major global cause of death, with uncontrolled hemorrhage as its leading preventable cause. Damage control resuscitation (DCR) is a cornerstone strategy for hemorrhagic shock, yet implementation varies by resource availability. This study compared DCR practices between high-income countries (HICs) and low- and middle-income countries (LMICs), predominantly represented by institutions from Latin
Lower content of cerebrospinal fluid chemokines in patients with cancer cachexia
Fortes, Marcos Fraga
Fortes, Marcos Fraga; Fortes, Gabriela Noronha; Fortes, Marcos Noronha; Gomes, Fernanda Christoffel; Seelaendar, Marilia; Pinho, Ariene Murari Soares De; Jesus, Joyce De Cassia Rosa De; Otoch, José Pinhata; ABSTRACT Purpose: Cancer-associated cachexia (CC) is characterized by involuntary weight loss and poor prognosis. Central nervous system (CNS) inflammation has been linked to CC symptoms. This study evaluated inflammatory mediators in the cerebrospinal fluid (CSF) of patients with CC. Methods: Volunteers were
Induced and spontaneous uterine leiomyomas in animal models: a scoping review
Sousa, Willane Bandeira de
Sousa, Willane Bandeira De; Nogueira Neto, João; Araújo, Kauã Manuel Costa; Gomes, Lyvia Maria Rodrigues De Sousa; Cartagenes, Maria Do Socorro De Sousa; Garcia, João Batista Santos; ABSTRACT Purpose: To map the experimental models of induced and spontaneous uterine leiomyomas (UL) in animals, describing induction techniques, evaluation methods, advantages, limitations, and research gaps. Methods: We conducted a systematic review of studies published between 2004 and 2024 with in-vivo animal experiments
Development and preliminary evaluation of a camera-assisted endovascular simulator using a three-dimensional printing
Andrade, Bruno Tavares de
Andrade, Bruno Tavares De; Lopes, Carlo Átila Holanda; Lima, Yury Tavares De; Pincanço, Victor Rocha; Bisio, Natan Rolim De Assunção; Sa, Henrique Luis Do Carmo E; Castro Neto, Josué Viana De; ABSTRACT Purpose: This study described the development and preliminary evaluation of a simulator that combines a three-dimensional-printed vascular model with a camera-assisted system for training basic endovascular skills. Methods: A hollow mannequin torso housed a transparent, three-dimensional-printed aorta. Guidewire
The beneficial effects of leave extract of Commiphora leptophloeos on intestinal mucositis induced by 5-fluorouracil in mice
Silva, Amanda Silveira da
Silva, Amanda Silveira Da; Barbosa, Stephannie Jamyla De Araújo; Ribeiro, Susana Barbosa; Carvalho, Lucas Vinicius Souza De; Silva, Rafaela Torres Dantas Da; Guerra, Gerlane Coelho Bernardo; Araújo Júnior, Raimundo Fernandes De; Silva, Nizyara Costa Da; Andrade, Raphael Victor Silva; Paiva, Gabrielle Marques De; Langassner, Silvana Maria Zucolotto; Dantas-Medeiros, Renato; Fé, Rafaela Alcindo Silva De Sousa; Lima, Maria Laura De Souza; Araújo, Aurigena Antunes De; ABSTRACT Purpose: This study aimed to
Effects of maternal arginine supplementation during lactation on offspring growth and wound healing in an experimental rat model of intrauterine malnutrition
Aranha Junior, Ayrton Alves
Aranha Junior, Ayrton Alves; Matias, Jorge Eduardo Fouto; Veronez, Djanira Aparecida Da Luz; Noronha, Lucia De; Repka, João Carlos; Aranha, Rafaella Toledo; Campos, Antônio Carlos Ligocki; ABSTRACT Purpose: To evaluate the effects of maternal arginine-enriched diet during lactation, following gestational undernutrition, on offspring growth and wound healing. Methods: Pregnant Wistar rats were divided into two groups during gestation: control (C; ad libitum diet) and undernourished (Und; 60% of control diet).
Latest news
The result of an experiment with rats brings histopathological and biochemical analysis focusing on the antifibrotic action of PEG 3350 in the case of liver injury induced by MTX and reveals the potential of polyethylene glycol in the fight against hepatotoxicity also caused by other substances that lead to oxidative stress of liver cells.
A drug used for the treatment of epilepsy it has demonstrated epigenetic properties, raising the possibility of use as an adjuvant, associated with chemo and radiotherapy for the treatment of tumors. A study with rats analyzed the inflammatory reaction, angiogenesis and collagen synthesis obtained from oral treatment in a skin lesion model.
By exploring the influence of milk fat globule protein - factor 8 (MFGE8), also known as lactaderin, results obtained through the RhoA/ROCK signaling pathway in an experiment with Sprague Dawley rats point to a decrease in oxidative stress and the inflammatory process, minimizing the impacts caused by trauma by protecting and restoring the barrier function of the intestinal mucosa.
In search of new alternatives for the treatment of portal hypertension, Brazilian researchers develop a pioneering study to validate a model in medium-sized animals, obtaining significant results for the improvement of the techniques applied in cases of gastrointestinal hemorrhage and indicating the direction for advances in diagnostic and therapeutic procedures.
Timeline
17 Sep 1987
SOBRADPEC installation
1989
I Congresso Nacional de Cirurgia Experimental - Maceió/AL
1991
II Congresso Nacional de Cirurgia Experimental - Foz do Iguaçu/PR
17 Sep 1997
SOBRADPEC turns 10 years old