Impact Factor
(JCR 2021)
1.564
Recent Publications
Holographic model of craniosynostosis for HoloLens
Yoshida, Mauricio Mitsuru; Freitas, André Luiz Pires De; Carvalho Júnior, José Da Conceição; Souza, Julio Sergio De; Baptista, Vinicius Santos; Ferreira, Lydia Masako; ABSTRACT Purpose: To develop a holographic skull model of a deformity resulting from craniosynostosis for the HoloLens. Methods: The methodology for product creation and prototyping was the design thinking structured with the double diamond. A desk survey was conducted with a literature review and an anteriority search.
Effect of multiorgan abdominal ischemic preconditioning on experimental kidney transplantation
Abate, Juan Cruz; Marinoff, Ivana Ivanoff; Arnal, Nathalie; Machuca, Mariana; Papa-Gobbi, Rodrigo; Vecchio, Leandro; Rumbo, Martín; Stringa, Pablo; Lausada, Natalia Raquel; ABSTRACT Purpose: To mitigate ischemia-reperfusion injury (IRI) triggered in solid organ transplant procedures, we aimed to evaluate the effects of multi-organ abdominal ischemic preconditioning (MAIP) in the context of renal IRI. Methods: An experimental kidney transplant model was conducted. Rats were divided into three groups: an intervention free basal
Naringin in cholestatic liver ischemia-reperfusion injury
Aslaner, Arif; Eyvaz, Kemal; Aydemir, Erhan; Yıldırım, Şenay; Kartal, Kübra Kılıç; Ellidağ, Hamit Yaşar; Doğan, Uğur; ABSTRACT Purpose: To evaluate the potential protective effects of naringin on liver by oxidative parameters and signal peptide-CUB-EGF-like domain-containing protein (SCUBE)-1 and 2 in an experimental cholestatic liver ischemia reperfusion (IR) model. Methods: Twenty-four female rats were divided into three groups; sham, control, and treatment. Groups 2 and 3 underwent bile duct ligation, and
Latest news
The result of an experiment with rats brings histopathological and biochemical analysis focusing on the antifibrotic action of PEG 3350 in the case of liver injury induced by MTX and reveals the potential of polyethylene glycol in the fight against hepatotoxicity also caused by other substances that lead to oxidative stress of liver cells.
A drug used for the treatment of epilepsy it has demonstrated epigenetic properties, raising the possibility of use as an adjuvant, associated with chemo and radiotherapy for the treatment of tumors. A study with rats analyzed the inflammatory reaction, angiogenesis and collagen synthesis obtained from oral treatment in a skin lesion model.
By exploring the influence of milk fat globule protein - factor 8 (MFGE8), also known as lactaderin, results obtained through the RhoA/ROCK signaling pathway in an experiment with Sprague Dawley rats point to a decrease in oxidative stress and the inflammatory process, minimizing the impacts caused by trauma by protecting and restoring the barrier function of the intestinal mucosa.
In search of new alternatives for the treatment of portal hypertension, Brazilian researchers develop a pioneering study to validate a model in medium-sized animals, obtaining significant results for the improvement of the techniques applied in cases of gastrointestinal hemorrhage and indicating the direction for advances in diagnostic and therapeutic procedures.
Timeline
17 Sep 1987
SOBRADPEC installation
1989
I Congresso Nacional de Cirurgia Experimental - Maceió/AL
1991
II Congresso Nacional de Cirurgia Experimental - Foz do Iguaçu/PR
17 Sep 1997
SOBRADPEC turns 10 years old
